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The control experiment that transformed an entire research field

Magdalena Götz, a professor of physiology at Ludwig Maximilian University of Munich, held the prestigious Segerfalk lecture 2021. (Photo: private) Magdalena Götz, a professor of physiology at Ludwig Maximilian University of Munich, held the prestigious Segerfalk lecture last year. The discovery she made as a young researcher started the new field of direct reprogramming to replace degenerated neur

https://www.medicine.lu.se/article/control-experiment-transformed-entire-research-field - 2025-09-05

Q&A: COVID-19 vaccine study gains attention

To the left: Petri dishes for cell cultures in the lab. To the right: Cells from the cell line the researchers used in the study. (Photo: Massimo De Marinis and Yang de Marinis) A new study from Lund University in Sweden on how the Pfizer-BioNTech COVID-19 vaccine affects human liver cells under experimental conditions, has been viewed more than 800,000 times in just over a week. The results have

https://www.medicine.lu.se/article/qa-covid-19-vaccine-study-gains-attention - 2025-09-05

The researcher supporting our athletes at the most successful Paralympic Winter Games in a long time

Kristina Fagher together with a Chinese colleague, "Ski-doctor", on the slopes. Meeting international colleagues is very rewarding and inspiring. Photo: Private photo. Our researcher is part of the Swedish Olympic Committee’s development programme “Tomorrow’s Sports Researchers” and her research on para-athletes’ health and wellbeing aims to ensure that people with physical disabilities can play s

https://www.medicine.lu.se/article/researcher-supporting-our-athletes-most-successful-paralympic-winter-games-long-time - 2025-09-05

Newly discovered drug candidate increases insulin secretion in type 2 diabetes

The islets of Langerhans are clusters of cells that are spread out over the pancreas. Lena Eliasson and Jones Ofori separate the islets of Langerhans from the pancreas to study them in the lab. Photo: Petra Olsson Researchers at Lund University have discovered increased levels of a microRNA in type 2 diabetes, which has a negative effect on insulin secretion. Their experiments on human insulin pro

https://www.medicine.lu.se/article/newly-discovered-drug-candidate-increases-insulin-secretion-type-2-diabetes - 2025-09-05

Young neurobiologists awarded grants for Alzheimer´s and Parkinson´s research

Image: Ben Sweet Two young experimental researchers have been awarded grants from the Anna-Lisa Rosenberg Foundation, the Department of Experimental Medical Science´s own grant for research in the neurobiological field with a clinical collaboration. Congratulations Alessandro Fiorenzano on the Anna-Lisa Rosengren Foundation grant, 65 000 SEK, how does it feel? – I am grateful for this fantastic op

https://www.medicine.lu.se/article/young-neurobiologists-awarded-grants-alzheimers-and-parkinsons-research - 2025-09-05

Psychiatric symptoms in Alzheimer´s disease

Photo: Mostphotos. In addition to memory problems and other cognitive symptoms, most people with Alzheimer’s disease also suffer from mental health issues. It has long been unclear whether these occur because of tissue changes in the brain, or whether they represent psychological reactions to cognitive symptoms. A study from Lund University in Sweden has provided new insight, and is published in B

https://www.medicine.lu.se/article/psychiatric-symptoms-alzheimers-disease - 2025-09-05

Brain plasticity and the link to depression

Illustration: iStock/koto_feja. This year's prestigious Segerfalk lecture will be given by Eero Castrén, Research Director at the Neuroscience Centre at the University of Helsinki. In his research on brain plasticity, he has discovered clues about which mechanisms in the brain are affected by antidepressants – and they could explain why these medicines work. Eero Castrén conducts research on brain

https://www.medicine.lu.se/article/brain-plasticity-and-link-depression - 2025-09-05

Metabolic BMI can predict the risk of type 2 diabetes in normal weight patients

Obesity and excess weight increase the risk of developing type 2 diabetes, but individuals of normal weight can also develop the disease. Researchers at Lund University in Sweden have discovered that it is possible to identify at-risk individuals by measuring BMI in a new way. The authors of the study have identified metabolic changes associated with obesity that can increase the risk of developin

https://www.medicine.lu.se/article/metabolic-bmi-can-predict-risk-type-2-diabetes-normal-weight-patients - 2025-09-05

Researchers search for answers to increase in acute severe hepatitis in children

Gülsen Özkaya Sahin (Photo: Tove Smeds) At the end of March, the first cases of acute severe hepatitis of unknown origin in children were reported in the UK. Since then, the number has increased to more than 300 in around 20 countries; there are now reports of nine suspected cases in Sweden. The acute liver infection mainly affects otherwise completely healthy children under the age of 16, which p

https://www.medicine.lu.se/article/researchers-search-answers-increase-acute-severe-hepatitis-children - 2025-09-05

Epigenetics can pave the way for individualised treatment of type 2 diabetes

Charlotte Ling, Tina Rönn and Karl Bacos carry out research at Lund University Diabetes Centre. They summarise some of the most important advancements within the field of epigenetics and diabetes in a review article. Photo: Petra Olsson Epigenetics has become an important tool for researchers endeavoring to understand the causes and development stages of type 2 diabetes. In the future, epigenetic

https://www.medicine.lu.se/article/epigenetics-can-pave-way-individualised-treatment-type-2-diabetes - 2025-09-05

WHO mission: creating evidence on how health care can prevent disease

Inger Kristensson Hallström and Hanne Tønnesen, head of the WHO Collaboratoring Centre at Lund University. Photo: Jon Ulvsgärd. One in three patients is asked about their lifestyle habits when they visit the outpatient healthcare clinics. This figure really ought to be higher, according to Professors Hanne Tønnesen and Inger Kristensson Hallström, who are in charge of the WHO Collaborating Centre

https://www.medicine.lu.se/article/who-mission-creating-evidence-how-health-care-can-prevent-disease - 2025-09-05

My aerobic capacity – RPC

Anita Wisén. Photo: Åsa Hansdotter. In order to be able to prescribe the appropriate dose of physical activity to patients, healthcare professionals need to consider a range of individual factors. There is a need to facilitate the assessment of aerobic capacity i. e. maximal oxygen uptake capacity (VO2max), as well as to calculate the intensity of training according to the WHO recommendations for

https://www.medicine.lu.se/article/my-aerobic-capacity-rpc - 2025-09-05

Awardees of the 2022 Bundy Academy Major Prize

Sebastian Palmqvist. The Bundy Academy’s 2022 major prize amounting to SEK 3 million is awarded to Sebastian Palmqvist, Associate Professor of Clinical Memory Research at Lund University and Senior Physician at the Memory Clinic at Skåne University Hospital, for his research on improved diagnostics of Alzheimer’s disease. RationaleSebastian Palmqvist has published a large number of research papers

https://www.medicine.lu.se/article/awardees-2022-bundy-academy-major-prize - 2025-09-05

Miniature bones as a research model for cancer

Paul Bourgine, researcher and Wallenberg Fellow in Molecular Medicine, has been awarded an ERC Proof of Concept, consisting of EUR 150,000. Photo: Kennet Ruona. By using cells isolated from cancer patients and mixing them with a new technology called “OssiGel”, it is possible to engineer human mini-bones. These miniaturized organs consist of mature bone and marrow tissue and can be used as model t

https://www.medicine.lu.se/article/miniature-bones-research-model-cancer - 2025-09-05

Newly discovered protein variants are key to insulin secretion

From left: Ewelina Golec, Ben King and Anna Blom, three of the researchers behind new findings on insulin secretion. Photo: Tove Smeds. Insulin secretion into the bloodstream requires a protein called CD59. New research led by Lund University shows that the two protein variants that are responsible for this function of CD59 are affected in diabetes. The study has been recently published in PNAS. I

https://www.medicine.lu.se/article/newly-discovered-protein-variants-are-key-insulin-secretion - 2025-09-05

Researchers reprogram human skin cells to aged neurons to study neurodegenerative disorders

Photo: iStock/Paul Campbell Researchers at Lund University in Sweden have developed a new method for studying age-related brain disorders. The researchers have focused on the neurodegenerative disorder Huntington’s disease and the results have now been published in the journal Brain. Basic medical research often faces the challenge of developing disease models that correspond to specific disease m

https://www.medicine.lu.se/article/researchers-reprogram-human-skin-cells-aged-neurons-study-neurodegenerative-disorders - 2025-09-05

The tumour environment can affect breast cancer prognosis

Photo: iStock/33karen33. The environment in which breast cancer arises –the interplay between the patient’s BMI, tumour size and cancer-specific proteins –is of importance for the prognosis. This is shown in a study from Lund University in Sweden. The knowledge could further enhance precision medicine in breast cancer. Major advances in diagnostics and treatment have improved survival rates among

https://www.medicine.lu.se/article/tumour-environment-can-affect-breast-cancer-prognosis - 2025-09-05

New treatment can result in access to more donor lungs and fewer complications after transplantations

Sandra Lindstedt, Snejana Hyllén, and Leif Pierre, Skåne University Hospital and Lund University. A large amount of lungs donated yearly cannot be used for transplantation. Researchers at Skåne University Hospital and Lund University have conducted an animal study with results that give hope that more donor lungs could be used to save lives in the future. The researchers have started a pilot study

https://www.medicine.lu.se/article/new-treatment-can-result-access-more-donor-lungs-and-fewer-complications-after-transplantations - 2025-09-05

SEK 40 million donation to the Faculty of Medicine

Photo: Kennet Ruona. In November 2021, a private foundation was established to promote scientific research in pancreatic cancer, gastroenterology, and pain management at Lund University. The foundation will be endowed with a total of SEK 40 million and will be managed by Lund University. Earlier this spring, the first grants from the foundation were distributed – approx. SEK 3 million will support

https://www.medicine.lu.se/article/sek-40-million-donation-faculty-medicine - 2025-09-05

Malin Parmar elected to the Royal Swedish Academy of Sciences

Malin Parmar. Photo: Kennet Ruona. The Royal Swedish Academy of Sciences has elected two new members of the Academy’s class for medical sciences. One of them is Malin Parmar, Professor of Cellular Neuroscience at Lund University. Together with her research group, Malin Parmar has conducted several groundbreaking studies on stem cells that have led to the development of new treatments for patients

https://www.medicine.lu.se/article/malin-parmar-elected-royal-swedish-academy-sciences - 2025-09-05